Getting the most out of treatment with ORSERDU

The patient brochure contains information to help you understand more about ORSERDU and why it may be the right treatment for you. It also has a space for you to write down questions so you can take them to your follow-up appointments.

Download the brochure

Questions you may have

It's important to communicate with your healthcare team regularly. Remember to speak up and ask any questions as they come up. Here are some to get you started:

  • How long can I expect to take ORSERDU?
  • What are the possible side effects?
  • Will I need to come into the clinic for any type of monitoring or testing?
  • Can I do anything to help manage side effects?
  • When should I contact the doctor or nurse?
  • What should I know or do before my next office visit?

Additional tips:

  • If possible, take a family member or friend to your appointments for support
  • Ask your healthcare team members to repeat or write down information
  • Before your next appointment, write down any changes to your overall health, treatment side effects, and/or changes in your daily routine

Some helpful resources

CANCERcare® Logo
CancerCare
Living Beyond Breast Cancer Logo
Living Beyond Breast
Cancer
Tigerlily Foundation Logo
Tigerlily Foundation

The above organizations provide support for cancer patients. This is not an exhaustive list. These organizations are independent from Stemline Therapeutics, Inc. ("Stemline"). Stemline has no financial interest in these organizations but may occasionally provide some financial support. All trademarks are property of their respective owners.

ER+, estrogen receptor-positive; ESR1, estrogen receptor 1; HER2-, human epidermal growth factor receptor 2-negative.

Savings and support

IMPORTANT SAFETY INFORMATION AND INDICATION

IMPORTANT SAFETY INFORMATION

ORSERDU may cause serious side effects, including:

  • Increased fat (lipid) levels in your blood (hypercholesterolemia and hypertriglyceridemia). Your healthcare provider will do blood tests to check your lipid levels before and during your treatment with ORSERDU

Before taking ORSERDU, tell your healthcare provider about all your medical conditions, including if you:

  • Have liver problems
  • Are pregnant or plan to become pregnant. ORSERDU can harm your unborn baby

      • Females who are able to become pregnant:

    • Your healthcare provider may do a pregnancy test before you start treatment with ORSERDU
    • You should use effective (contraception) birth control during treatment with ORSERDU and for 1 week after the last dose
    • Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with ORSERDU

      • Males with female partners who are able to become pregnant:

    • You should use effective (contraception) birth control during treatment with ORSERDU and for 1 week after the last dose
  • Are breastfeeding or plan to breastfeed. It is not known if ORSERDU passes into your breast milk. Do not breastfeed during treatment with ORSERDU and for 1 week after the last dose

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. ORSERDU and other medicines may affect each other causing side effects. Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get a new medicine.

The most common side effects of ORSERDU include:

  • Muscle and joint (musculoskeletal) pain
  • Nausea
  • Increased cholesterol and triglyceride levels in your blood
  • Increased liver function tests
  • Tiredness
  • Decreased red blood cell counts
  • Vomiting
  • Decreased salt (sodium) levels in your blood
  • Increased kidney function test
  • Decreased appetite
  • Diarrhea
  • Headache
  • Constipation
  • Stomach-area (abdominal) pain
  • Hot flush
  • Indigestion or heartburn

Your healthcare provider may decrease your dose, temporarily stop, or completely stop treatment with ORSERDU, if you develop certain side effects.

ORSERDU may affect fertility in males and in females who are able to become pregnant. Talk to your healthcare provider if this is a concern for you.

These are not all the possible side effects of ORSERDU. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

INDICATION

ORSERDU (elacestrant), 345 mg tablets, is a prescription medicine to treat women who have gone through menopause and adult men with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, ESR1-mutated advanced breast cancer or breast cancer that has spread to other parts of the body (metastatic), and whose disease has progressed after endocrine therapy.

Your healthcare provider will perform a test to make sure that ORSERDU is right for you.

It is not known if ORSERDU is safe and effective in children.

Please see full Prescribing Information, including Patient Information.